Hypocomplementaemic immune complex tubulointerstitial nephritis
نویسندگان
چکیده
منابع مشابه
Hypocomplementaemic immune complex tubulointerstitial nephritis
We report a rare cause of rapidly progressive renal failure associated with low complement, positive ANA but negative anti DS-DNA. A renal biopsy demonstrated tubulointerstitial nephritis with positive immunoglobulin staining involving the interstitium and tubular basement membrane but glomerular sparing. A review of the literature and differential diagnosis are discussed.
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Dear Sir, We read with great interest the paper of Gupta et al. concerning a case of hypocomplementaemic tubulointerstitial nephritis (TIN) [1]. Hypocomplementaemic immune complex TIN in the absence of autoimmune disorders is a rare condition, and only a limited number of cases have been reported, of which most have been labelled idiopathic [2]. However, in recent years, several case reports an...
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A 59-year-old man was diagnosed with IgG4-related tubulointerstitial nephritis. His symptoms as well as laboratory and imaging findings were improved after initiation of steroid therapy. Serologically, he showed hypocomplementemia (C3 23 mg/dl, C4 <2 mg/dl, CH50 <7 U/ml) with high levels of IgG (IgG4 1,970 mg/dl) and immune complexes (C1q assay 8.1 μg/ml) and a low level of C1q (<2.0 mg/dl). Hi...
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ژورنال
عنوان ژورنال: Clinical Kidney Journal
سال: 2009
ISSN: 2048-8505,2048-8513
DOI: 10.1093/ndtplus/sfp141